Small molecules which reverse PAX3 Knock-in
Canned Analysis
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General Information
AccessionDCA00023612
TitleSmall molecules which reverse PAX3 Knock-in
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PAX3 Knock-in in the Palatal shelves (E14.5 embryos - palate) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23754e467bea600fbb9a4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:625
Cell TypePalatal shelves (E14.5 embryos - palate)
Gene Symbol (human)PAX3
Gene Symbol (mouse)Pax3
Organismmouse
Perturbation TypeKnock-in
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM287783, GSM287784, GSM287787, GSM287788
Perturbed SamplesGSM287781, GSM287782, GSM287785, GSM287786
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11400
Gene Expression Omnibus
Transcription factor paired box 3 knockin embryos: palate
7
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