Small molecules which reverse SP3 Deficiency
Canned Analysis
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General Information
AccessionDCA00023626
TitleSmall molecules which reverse SP3 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SP3 Deficiency in the Embryonic heart (day 12.5 C57Bl/6) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d231dfe467bea600fbb73a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:637
Cell TypeEmbryonic heart (day 12.5 C57Bl/6)
Gene Symbol (human)SP3
Gene Symbol (mouse)Sp3
Organismmouse
Perturbation TypeDeficiency
None{u'vals': [-0.0453292510202, -0.0423567648372, 0.0413601243931, -0.0409552186474, -0.0385082422312, -0.0375784412915, -0.0368527732649, 0.0365370621547, 0.0361261933007, -0.0359494945356, -0.0358988992464, 0.0351522132859, 0.0346144120186, 0.0344866717076
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM230957, GSM230959, GSM230960
Perturbed SamplesGSM230954, GSM230955, GSM230956
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9124
Gene Expression Omnibus
Transcription factor Sp3 deficiency effect on the embryonic heart
7
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