Small molecules which reverse DMD Deficiency
Canned Analysis
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General Information
AccessionDCA00023634
TitleSmall molecules which reverse DMD Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DMD Deficiency in the Cardiac muscles from 10.5-month (mdx animals) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f3ace467bea600fb9c54
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:641
Cell TypeCardiac muscles from 10.5-month (mdx animals)
Gene Symbol (human)DMD
Gene Symbol (mouse)Dmd
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM24800, GSM24801, GSM24802
Perturbed SamplesGSM24803, GSM24804, GSM24805
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1471
Gene Expression Omnibus
Dystrophin deficiency effect on cardiac muscles: time course
14
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