Small molecules which mimic GLI1 INHIBITION
Canned Analysis
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General Information
AccessionDCA00023637
TitleSmall molecules which mimic GLI1 INHIBITION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GLI1 INHIBITION in the Panc-1 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f398e467bea600fb9c4a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvmathur
CREEDS IDgene:643
Cell TypePanc-1 cells
Gene Symbol (human)GLI1
Gene Symbol (mouse)Gli1
Organismhuman
Perturbation TypeINHIBITION
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM904693, GSM904694, GSM904695
Perturbed SamplesGSM904696, GSM904697, GSM904698
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE36855
Gene Expression Omnibus
Gli transcriptional repressor Gli3T effect on epithelioid carcinoma cell line Panc-1
7
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