Small molecules which mimic GATA3 Ectopic expression
Canned Analysis
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General Information
AccessionDCA00023643
TitleSmall molecules which mimic GATA3 Ectopic expression
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GATA3 Ectopic expression in the Basal Breast Cancer Cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f37be467bea600fb9c3e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvmathur
CREEDS IDgene:649
Cell TypeBasal Breast Cancer Cells
Gene Symbol (human)GATA3
Gene Symbol (mouse)Gata3
Organismhuman
Perturbation TypeEctopic expression
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM596523, GSM596524, GSM596525
Perturbed SamplesGSM596526, GSM596527, GSM596528
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE24249
Gene Expression Omnibus
GATA3 ectopic expression effect on MDA-MB-231 breast cancer cells
7
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