Small molecules which reverse CTNNB1 Inactivation
Canned Analysis
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General Information
AccessionDCA00023646
TitleSmall molecules which reverse CTNNB1 Inactivation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CTNNB1 Inactivation in the Intestinal crypts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23cafe467bea600fbbc00
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:655
Cell TypeIntestinal crypts
Gene Symbol (human)CTNNB1
Organismmouse
Perturbation Type Inactivation
None{u'vals': [0.0500271351399, 0.0470078683888, 0.0463499929723, 0.0421347298706, 0.0410327840723, 0.0404728999582, 0.037450802955, 0.0366356547004, -0.0361597994871, 0.0355114987508, 0.035488414554, 0.0347484857954, 0.0336043791938, -0.0334287414501, 0.0333
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM219114, GSM219115
Perturbed SamplesGSM219116, GSM219117
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8818
Gene Expression Omnibus
Beta-catenin inactivation effect on intestinal crypts
7
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