Small molecules which reverse ARHGDIB KD
Canned Analysis
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General Information
AccessionDCA00023662
TitleSmall molecules which reverse ARHGDIB KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ARHGDIB KD in the MDA-MB-231 breast cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ff0de467bea600fba110
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:661
Cell TypeMDA-MB-231 breast cancer cells
Gene Symbol (human)ARHGDIB
Gene Symbol (mouse)Arhgdib
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM200678, GSM200681, GSM200683
Perturbed SamplesGSM200680, GSM200682, GSM200684
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE8087
Gene Expression Omnibus
RhoGDIbeta depletion effect on breast cancer cell line
7
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