Small molecules which reverse NOTCH1 Deficiency
Canned Analysis
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General Information
AccessionDCA00023664
TitleSmall molecules which reverse NOTCH1 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by NOTCH1 Deficiency in the Hair follicles cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ff29e467bea600fba11c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:662
Cell TypeHair follicles
Gene Symbol (human)NOTCH1
Gene Symbol (mouse)Notch1
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM158362, GSM158363
Perturbed SamplesGSM158359, GSM158361
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE6867
Gene Expression Omnibus
Notch1 deficiency effect on hair follicles
7
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