Small molecules which reverse MYD88 Deficiency
Canned Analysis
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General Information
AccessionDCA00023692
TitleSmall molecules which reverse MYD88 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by MYD88 Deficiency in the LUNG cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f8d5e467bea600fb9e58
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:679
Cell TypeLUNG
Gene Symbol (human)MYD88
Gene Symbol (mouse)Myd88
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM154451, GSM154452, GSM154453
Perturbed SamplesGSM154443, GSM154444, GSM154446
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6688
Gene Expression Omnibus
Signal transduction adaptor MyD88 deficient lung response to Chlamydia pneumoniae infection
7
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