Small molecules which mimic CREB1 DEPLETION
Canned Analysis
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General Information
AccessionDCA00023693
TitleSmall molecules which mimic CREB1 DEPLETION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by CREB1 DEPLETION in the K562 myeloid leukemia cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f111e467bea600fb9b32
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:68
Cell TypeK562 myeloid leukemia cell line
Gene Symbol (human)CREB1
Gene Symbol (mouse)Creb1
Organismhuman
Perturbation TypeDEPLETION
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM304303, GSM304304, GSM304479, GSM304480, GSM304481, GSM304482, GSM304483, GSM304484, GSM304486, GSM304498
Perturbed SamplesGSM304487, GSM304488, GSM304489, GSM304490, GSM304491, GSM304492, GSM304493, GSM304494, GSM304495, GSM304496
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE12056
Gene Expression Omnibus
Transcription factor CREB depletion effect on myeloid leukemic cell line
7
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