Small molecules which mimic HDAC2 Deficiency
Canned Analysis
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General Information
AccessionDCA00023697
TitleSmall molecules which mimic HDAC2 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HDAC2 Deficiency in the Embryonic heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1ff72e467bea600fba13a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:685
Cell TypeEmbryonic heart
Gene Symbol (human)HDAC2
Gene Symbol (mouse)Hdac2
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM156165, GSM156167
Perturbed SamplesGSM156166, GSM156168
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE6770
Gene Expression Omnibus
Histone deacetylase-2 deficiency effect on the embryonic heart
7
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