Small molecules which reverse ATM KD
Canned Analysis
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General Information
AccessionDCA00023704
TitleSmall molecules which reverse ATM KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ATM KD in the MCF-10A cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f903e467bea600fb9e6c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCopernicia
CREEDS IDgene:690
Cell TypeMCF-10A
Gene Symbol (human)ATM
Gene Symbol (mouse)Atm
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1311313, GSM1311314, GSM1311315
Perturbed SamplesGSM1311322, GSM1311323, GSM1311324
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54268
Gene Expression Omnibus
Expression data of ATM, ATR, CHK1, CHK2, and 53BP1 shRNA knockdown and control shRNA in MCF-10A cells
70
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