Small molecules which reverse PTPN1 KD
Canned Analysis
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General Information
AccessionDCA00023726
TitleSmall molecules which reverse PTPN1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PTPN1 KD in the KM-H2 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23322e467bea600fbb7c8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCopernicia
CREEDS IDgene:700
Cell TypeKM-H2
Gene Symbol (human)PTPN1
Gene Symbol (mouse)Ptpn1
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1308975, GSM1308976
Perturbed SamplesGSM1308977, GSM1308978
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE54157
Gene Expression Omnibus
PTPN1 depletion effect on Hodgkin lymphoma derived cell line
7
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