Small molecules which mimic PARP2 KD
Canned Analysis
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General Information
AccessionDCA00023727
TitleSmall molecules which mimic PARP2 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PARP2 KD in the HepG2 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d23316e467bea600fbb7c2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCopernicia
CREEDS IDgene:703
Cell TypeHepG2
Gene Symbol (human)PARP2
Gene Symbol (mouse)Parp2
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1076044, GSM1076045, GSM1076046
Perturbed SamplesGSM1076047, GSM1076048, GSM1076049
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43981
Gene Expression Omnibus
Depletion of PARP-2 in HepG2 cells
7
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