Small molecules which reverse ZFP36 Deficiency
Canned Analysis
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General Information
AccessionDCA00023740
TitleSmall molecules which reverse ZFP36 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ZFP36 Deficiency in the Fibroblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22cbce467bea600fbb4fa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:734
Cell TypeFibroblasts
Gene Symbol (human)ZFP36
Gene Symbol (mouse)Zfp36
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM120234, GSM120244, GSM120254, GSM120263, GSM120272
Perturbed SamplesGSM120229, GSM120239, GSM120249, GSM120259
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE5324
Gene Expression Omnibus
Tristetrapolin-deficiency and mRNA decay in fibroblasts: time course
21
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