Small molecules which reverse PPP1R1A KO
Canned Analysis
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General Information
AccessionDCA00023742
TitleSmall molecules which reverse PPP1R1A KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PPP1R1A KO in the hippocampus cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22cb3e467bea600fbb4f6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorudicuty
CREEDS IDgene:735
Cell Typehippocampus
Gene Symbol (human)PPP1R1A
Gene Symbol (mouse)Ppp1r1a
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM92512, GSM92513, GSM92514
Perturbed SamplesGSM92515, GSM92516, GSM92517
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4040
Gene Expression Omnibus
Inhibitor-1 knockout effect on the hippocampus
7
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