Small molecules which mimic HDAC9 INHIBITION - trichostatin A
Canned Analysis
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General Information
AccessionDCA00023743
TitleSmall molecules which mimic HDAC9 INHIBITION - trichostatin A
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by HDAC9 INHIBITION - trichostatin A in the Endothelial cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22ca7e467bea600fbb4f0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:736
Cell TypeEndothelial cells
Gene Symbol (human)HDAC9
Gene Symbol (mouse)Hdac9
Organismhuman
Perturbation TypeINHIBITION - trichostatin A
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM136682, GSM136696, GSM136697
Perturbed SamplesGSM136698, GSM136700, GSM136702
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5856
Gene Expression Omnibus
Histone deacetylase inhibitor effect on endothelial cells
7
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