Small molecules which reverse CHRNB4 Deficiency
Canned Analysis
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General Information
AccessionDCA00023756
TitleSmall molecules which reverse CHRNB4 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CHRNB4 Deficiency in the Brain cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21c88e467bea600fbadda
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:741
Cell TypeBrain
Gene Symbol (human)CHRNB4
Gene Symbol (mouse)Chrnb4
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM120574, GSM120575, GSM120576, GSM120577, GSM120578, GSM120579
Perturbed SamplesGSM120580, GSM120581, GSM120582, GSM120583, GSM120584
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5320
Gene Expression Omnibus
Beta-4 nicotinic acetylcholine receptor subunit deficiency effect on the brain
6
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