Small molecules which reverse PPARGC1A NULL MUTATION
Canned Analysis
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General Information
AccessionDCA00023760
TitleSmall molecules which reverse PPARGC1A NULL MUTATION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PPARGC1A NULL MUTATION in the Brown adipocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21c34e467bea600fbadb6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:748
Cell TypeBrown adipocyte
Gene Symbol (human)PPARGC1A
Gene Symbol (mouse)Ppargc1a
Organismmouse
Perturbation TypeNULL MUTATION
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM113409, GSM113411
Perturbed SamplesGSM113457, GSM113458
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5041
Gene Expression Omnibus
PGC-1alpha null brown adipocyte response to cAMP
7
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