Small molecules which reverse LAMA2 Deficiency
Canned Analysis
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General Information
AccessionDCA00023776
TitleSmall molecules which reverse LAMA2 Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by LAMA2 Deficiency in the Diaphragm (from dystrophia muscularis -dy/dy- mouse model) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d215e4e467bea600fbab1a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:774
Cell TypeDiaphragm (from dystrophia muscularis -dy/dy- mouse model)
Gene Symbol (human)LAMA2
Gene Symbol (mouse)Lama2
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM73331, GSM73332, GSM73333, GSM73334
Perturbed SamplesGSM73335, GSM73336, GSM73337, GSM73338
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3252
Gene Expression Omnibus
Alpha2-laminin deficient dy/dy model of muscular dystrophy: diaphragm
12
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