Small molecules which mimic LHX1 NULL MUTATION - Ablation
Canned Analysis
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General Information
AccessionDCA00023779
TitleSmall molecules which mimic LHX1 NULL MUTATION - Ablation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by LHX1 NULL MUTATION - Ablation in the Embryonic kidneys (from day E18.5) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d215d0e467bea600fbab10
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:776
Cell TypeEmbryonic kidneys (from day E18.5)
Gene Symbol (human)LHX1
Gene Symbol (mouse)Lhx1
Organismmouse
Perturbation TypeNULL MUTATION - Ablation
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM96567, GSM96568
Perturbed SamplesGSM96569, GSM96570
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE4230
Gene Expression Omnibus
Homeobox Lim1 mutant nephron-deficient kidneys
14
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