Small molecules which reverse CTNNB1 Activation (deltaNB-cateninER transgenics)
Canned Analysis
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General Information
AccessionDCA00023802
TitleSmall molecules which reverse CTNNB1 Activation (deltaNB-cateninER transgenics)
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CTNNB1 Activation (deltaNB-cateninER transgenics) in the Skin - 1 Day cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d214d0e467bea600fbaaa2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:794
Cell TypeSkin - 1 Day
Gene Symbol (human)CTNNB1
Organismmouse
Perturbation TypeActivation (deltaNB-cateninER transgenics)
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM26948, GSM26949, GSM26950
Perturbed SamplesGSM26939, GSM26940, GSM26941
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE1579
Gene Expression Omnibus
Beta-catenin activation effect on skin: time course
21
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