Small molecules which mimic DROSHA KD
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00023809
TitleSmall molecules which mimic DROSHA KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by DROSHA KD in the HeLa cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d218d3e467bea600fbac68
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlkwhite
CREEDS IDgene:805
Cell TypeHeLa
Gene Symbol (human)DROSHA
Gene Symbol (mouse)Drosha
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM155730, GSM155731
Perturbed SamplesGSM155732, GSM155733
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE6767
Gene Expression Omnibus
Drosha knockdown in human cells reduces viability but does not affect snRNA or rRNA synthesis or processing
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.