Small molecules which reverse CIITA KD
Canned Analysis
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General Information
AccessionDCA00023818
TitleSmall molecules which reverse CIITA KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CIITA KD in the KMH2 cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d212a9e467bea600fba9b2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlkwhite
CREEDS IDgene:811
Cell TypeKMH2 cells
Gene Symbol (human)CIITA
Gene Symbol (mouse)Ciita
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM637966, GSM637967
Perturbed SamplesGSM637968, GSM637969
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25987
Gene Expression Omnibus
Gene expression profiling of Hodgkin lymphoma cell line KMH2: Comparison of CIITA-BX648577 knockdown cultures with non-silencing controls
7
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