Small molecules which reverse RRM2B KD
Canned Analysis
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General Information
AccessionDCA00023822
TitleSmall molecules which reverse RRM2B KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RRM2B KD in the human oropharyngea carcinoma KB cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d212b9e467bea600fba9ba
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlkwhite
CREEDS IDgene:815
Cell Typehuman oropharyngea carcinoma KB cells
Gene Symbol (human)RRM2B
Gene Symbol (mouse)Rrm2b
Organismhuman
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM621124, GSM621125
Perturbed SamplesGSM621126, GSM621127
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25238
Gene Expression Omnibus
Gene expression profile associated with p53R2 in human cancer cells
7
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