Small molecules which mimic PPIB Depletion
Canned Analysis
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General Information
AccessionDCA00023823
TitleSmall molecules which mimic PPIB Depletion
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by PPIB Depletion in the U251 glioblastoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2128ae467bea600fba9a4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorudicuty
CREEDS IDgene:818
Cell TypeU251 glioblastoma cells
Gene Symbol (human)PPIB
Gene Symbol (mouse)Ppib
Organismhuman
Perturbation TypeDepletion
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM1228046, GSM1228047, GSM1228048
Perturbed SamplesGSM1228049, GSM1228050, GSM1228051
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE50756
Gene Expression Omnibus
Cyclophilin B depletion effect on glioblastoma multiforme cell line
7
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