Small molecules which reverse PARK2 OE
Canned Analysis
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General Information
AccessionDCA00023826
TitleSmall molecules which reverse PARK2 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PARK2 OE in the U87MG cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21a61e467bea600fbad16
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvirginia
CREEDS IDgene:82
Cell TypeU87MG
Gene Symbol (human)PARK2
Gene Symbol (mouse)Park2
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM729727, GSM729728, GSM729729, GSM729730, GSM729731, GSM729732, GSM729733, GSM729734, GSM729735, GSM729736, GSM729737, GSM729738
Perturbed SamplesGSM729739, GSM729740, GSM729741, GSM729742, GSM729743, GSM729744, GSM729745, GSM729746, GSM729747
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE29494
Gene Expression Omnibus
Parkin expression in parkin-deficient U87MG glioma cells
7
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