Small molecules which reverse RRP1B OE
Canned Analysis
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General Information
AccessionDCA00023830
TitleSmall molecules which reverse RRP1B OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by RRP1B OE in the cell line MDA-MB-231 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20ceee467bea600fba72e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormtahay
CREEDS IDgene:821
Cell Typecell line MDA-MB-231
Gene Symbol (human)RRP1B
Gene Symbol (mouse)Rrp1b
Organismhuman
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1304753, GSM1304754, GSM1304755, GSM1304756, GSM1304757
Perturbed SamplesGSM1304748, GSM1304749, GSM1304750, GSM1304751, GSM1304752
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE53979
Gene Expression Omnibus
Expression data from MDA-MB-231 cells over-expressing RRP1B and MDA-MB-231 control cells with endogenous RRP1B levels
7
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