Small molecules which mimic GATA4 ablation S105 phosphorylation site
Canned Analysis
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General Information
AccessionDCA00023839
TitleSmall molecules which mimic GATA4 ablation S105 phosphorylation site
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GATA4 ablation S105 phosphorylation site in the heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d207ede467bea600fba4f8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcms
CREEDS IDgene:837
Cell Typeheart
Gene Symbol (human)GATA4
Gene Symbol (mouse)Gata4
Organismmouse
Perturbation Typeablation S105 phosphorylation site
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM751508, GSM751509
Perturbed SamplesGSM751512, GSM751513
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE30314
Gene Expression Omnibus
Adrenergic stress effect on transcription factor GATA4 S105A mutants: heart ventricle
14
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