Small molecules which mimic GATA4 ablation S105 phosphorylation site
Canned Analysis
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General Information
AccessionDCA00023841
TitleSmall molecules which mimic GATA4 ablation S105 phosphorylation site
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by GATA4 ablation S105 phosphorylation site in the heart treated with pseudoephedrine cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20800e467bea600fba500
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcms
CREEDS IDgene:838
Cell Typeheart treated with pseudoephedrine
Gene Symbol (human)GATA4
Gene Symbol (mouse)Gata4
Organismmouse
Perturbation Typeablation S105 phosphorylation site
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM751510, GSM751511
Perturbed SamplesGSM751514, GSM751515
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30314
Gene Expression Omnibus
Adrenergic stress effect on transcription factor GATA4 S105A mutants: heart ventricle
14
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