Small molecules which reverse EMD KO
Canned Analysis
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General Information
AccessionDCA00023844
TitleSmall molecules which reverse EMD KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by EMD KO in the heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d20d18e467bea600fba742
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcms
CREEDS IDgene:839
Cell Typeheart
Gene Symbol (human)EMD
Gene Symbol (mouse)Emd
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM147451, GSM147452, GSM147459, GSM147460, GSM147461, GSM147462, GSM147463, GSM147465
Perturbed SamplesGSM147466, GSM147467, GSM147468, GSM147469, GSM147481, GSM147493
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6399
Gene Expression Omnibus
X-linked Emery-Dreifuss muscular dystrophy model and cardiomyopathy
12
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