Small molecules which reverse LMX1B KO
Canned Analysis
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General Information
AccessionDCA00023846
TitleSmall molecules which reverse LMX1B KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by LMX1B KO in the embryonic (e11.5) proximal hindlimb bud tissues cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21a74e467bea600fbad1e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:84
Cell Typeembryonic (e11.5) proximal hindlimb bud tissues
Gene Symbol (human)LMX1B
Gene Symbol (mouse)Lmx1b
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM264689, GSM264690, GSM264691
Perturbed SamplesGSM264692, GSM264693, GSM264694
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10516
Gene Expression Omnibus
Lmx1b knockout effect on embryonic proximal hindlimb buds
7
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