Small molecules which reverse SRF NULL MUTATION
Canned Analysis
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General Information
AccessionDCA00023854
TitleSmall molecules which reverse SRF NULL MUTATION
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SRF NULL MUTATION in the Neonatal cardiomyocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fd04e467bea600fba028
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:851
Cell TypeNeonatal cardiomyocytes
Gene Symbol (human)SRF
Gene Symbol (mouse)Srf
Organismmouse
Perturbation TypeNULL MUTATION
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM71592, GSM71606, GSM71608
Perturbed SamplesGSM71610, GSM71612, GSM71613
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3181
Gene Expression Omnibus
Serum response factor null mutation effect on neonatal cardiomyocytes
7
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