Small molecules which mimic IFNAR1 KO
Canned Analysis
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General Information
AccessionDCA00023885
TitleSmall molecules which mimic IFNAR1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by IFNAR1 KO in the B cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f12ee467bea600fb9b3e
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatordsurujon
CREEDS IDgene:879
Cell TypeB cells
Gene Symbol (human)IFNAR1
Gene Symbol (mouse)Ifnar1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM71996, GSM71997, GSM71998, GSM71999
Perturbed SamplesGSM72000, GSM72001, GSM72002, GSM72003
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3203
Gene Expression Omnibus
Interferon receptor deficient lymph node B cell response to influenza infection
14
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