Small molecules which reverse DMD KO
Canned Analysis
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General Information
AccessionDCA00023890
TitleSmall molecules which reverse DMD KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DMD KO in the muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f60fe467bea600fb9d5c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatordsurujon
CREEDS IDgene:880
Cell Typemuscle
Gene Symbol (human)DMD
Gene Symbol (mouse)Dmd
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM4372, GSM4373, GSM4374, GSM4375, GSM4376
Perturbed SamplesGSM4377, GSM4378, GSM4379, GSM4380, GSM4381
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE466
Gene Expression Omnibus
Dystrophin-deficient mdx muscle regeneration
12
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