Small molecules which reverse DICER1 KD
Canned Analysis
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General Information
AccessionDCA00023898
TitleSmall molecules which reverse DICER1 KD
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by DICER1 KD in the Thymocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f0d6e467bea600fb9b18
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorshvetank
CREEDS IDgene:891
Cell TypeThymocytes
Gene Symbol (human)DICER1
Gene Symbol (mouse)Dicer1
Organismmouse
Perturbation TypeKD
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM1384042, GSM1384043, GSM1384044
Perturbed SamplesGSM1384039, GSM1384040, GSM1384041
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE57511
Gene Expression Omnibus
Gene expression profile of Dicer knockout in mouse DP thymocytes
7
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