Small molecules which reverse SOD1 G93A mutation
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00023904
TitleSmall molecules which reverse SOD1 G93A mutation
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by SOD1 G93A mutation in the oculomotor neurons 10 week cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1f0dee467bea600fb9b1c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcms
CREEDS IDgene:897
Cell Typeoculomotor neurons 10 week
Gene Symbol (human)SOD1
Gene Symbol (mouse)Sod1
Organismmouse
Perturbation TypeG93A mutation
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM75472, GSM75479, GSM75484
Perturbed SamplesGSM75488, GSM75489, GSM75490
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3343
Gene Expression Omnibus
SOD1-G93A transgenic model of amyotrophic lateral sclerosis: oculomotor nucleus
24
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.