Small molecules which mimic APP OE
Canned Analysis
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General Information
AccessionDCA00023909
TitleSmall molecules which mimic APP OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by APP OE in the Hippocampi cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21fcfe467bea600fbaf44
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:900
Cell TypeHippocampi
Gene Symbol (human)APP
Gene Symbol (mouse)App
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM26706, GSM26707
Perturbed SamplesGSM26708, GSM26709
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1556
Gene Expression Omnibus
Amyloid precursor protein mutant overexpression in strain resistant to neuronal cell loss
7
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