Small molecules which reverse ESR2 KO
Canned Analysis
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General Information
AccessionDCA00023912
TitleSmall molecules which reverse ESR2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by ESR2 KO in the Skeletal muscle (C57BL/6) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21fdae467bea600fbaf4a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:901
Cell TypeSkeletal muscle (C57BL/6)
Gene Symbol (human)ESR2
Gene Symbol (mouse)Esr2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM16989, GSM16990, GSM16991
Perturbed SamplesGSM16992, GSM16993, GSM16994
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1050
Gene Expression Omnibus
Estrogen receptor beta knockout effect on skeletal muscle
7
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