Small molecules which mimic DMD Deficiency
Canned Analysis
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General Information
AccessionDCA00023919
TitleSmall molecules which mimic DMD Deficiency
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by DMD Deficiency in the Extensor digitorum longus (mdx mice) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21fb3e467bea600fbaf38
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:905
Cell TypeExtensor digitorum longus (mdx mice)
Gene Symbol (human)DMD
Gene Symbol (mouse)Dmd
Organismmouse
Perturbation TypeDeficiency
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM13672, GSM13673
Perturbed SamplesGSM13667, GSM13670
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE897
Gene Expression Omnibus
Dystrophin-deficient mdx, mdx5cv and wild type skeletal muscle profiles
84
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