Small molecules which mimic ADRB2 KO
Canned Analysis
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General Information
AccessionDCA00023969
TitleSmall molecules which mimic ADRB2 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ADRB2 KO in the hearth tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d22f04e467bea600fbb5f8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:935
Cell Typehearth tissue
Gene Symbol (human)ADRB2
Gene Symbol (mouse)Adrb2
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM311495, GSM311496, GSM311497, GSM311498, GSM311499, GSM311500, GSM311501, GSM311502, GSM311503, GSM311504
Perturbed SamplesGSM311560, GSM311561, GSM311562, GSM311563, GSM311564, GSM311565, GSM311566, GSM311567, GSM311568, GSM311569
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE12413
Gene Expression Omnibus
Catecholamine stress effect on hearts of beta2 adrenergic receptor deficient mutants
7
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