Small molecules which reverse HDAC1 KO
Canned Analysis
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General Information
AccessionDCA00023980
TitleSmall molecules which reverse HDAC1 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by HDAC1 KO in the embryonic stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d21443e467bea600fbaa66
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:94
Cell Typeembryonic stem cells
Gene Symbol (human)HDAC1
Gene Symbol (mouse)Hdac1
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM130365, GSM130366, GSM130367
Perturbed SamplesGSM130368, GSM130369, GSM130370
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE5583
Gene Expression Omnibus
Histone deacetylase 1 deficient embryonic stem cells
7
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