Small molecules which reverse PMP22 OE
Canned Analysis
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General Information
AccessionDCA00023988
TitleSmall molecules which reverse PMP22 OE
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by PMP22 OE in the sciatic nerve cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d2085ee467bea600fba52a
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:945
Cell Typesciatic nerve
Gene Symbol (human)PMP22
Gene Symbol (mouse)Pmp22
Organismmouse
Perturbation TypeOE
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM34798, GSM34799, GSM34800
Perturbed SamplesGSM34807, GSM34808, GSM34809
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1947
Gene Expression Omnibus
Peripheral myelin protein 22 gene dosage and point mutation effect on sciatic nerve
63
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