Small molecules which mimic ADAM10 KO
Canned Analysis
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General Information
AccessionDCA00024009
TitleSmall molecules which mimic ADAM10 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by ADAM10 KO in the skin cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fc4de467bea600fb9fda
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorlhs
CREEDS IDgene:982
Cell Typeskin
Gene Symbol (human)ADAM10
Gene Symbol (mouse)Adam10
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM625965, GSM625966, GSM625967, GSM625968
Perturbed SamplesGSM625969, GSM625970, GSM625971, GSM625972
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE25480
Gene Expression Omnibus
Adam10 deficiency effect on the epidermis
7
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