Small molecules which reverse EIF2AK3 KO
Canned Analysis
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General Information
AccessionDCA00024012
TitleSmall molecules which reverse EIF2AK3 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by EIF2AK3 KO in the Pancreas cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d1fc59e467bea600fb9fe0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorshvetank
CREEDS IDgene:983
Cell TypePancreas
Gene Symbol (human)EIF2AK3
Gene Symbol (mouse)Eif2ak3
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM99696, GSM99762, GSM99776, GSM99780
Perturbed SamplesGSM99695, GSM99698, GSM99716, GSM99777
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4422
Gene Expression Omnibus
PERK role in the exocrine pancreas
7
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