Small molecules which mimic XRCC5 KO
Canned Analysis
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General Information
AccessionDCA00024015
TitleSmall molecules which mimic XRCC5 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which mimic the gene expression signature induced by XRCC5 KO in the germ cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d202efe467bea600fba2c8
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:995
Cell Typegerm cells
Gene Symbol (human)XRCC5
Gene Symbol (mouse)Xrcc5
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionmimic
Characteristic Direction parameters
Control SamplesGSM47433, GSM47434
Perturbed SamplesGSM47429, GSM47430
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Datasets used in the analysis
Keyword
Tool Name
GSE2498
Gene Expression Omnibus
Telomere dysfunction effect on male germ cells
14
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