Small molecules which reverse CLCN5 KO
Canned Analysis
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General Information
AccessionDCA00024020
TitleSmall molecules which reverse CLCN5 KO
DescriptionThe L1000 database was queried in order to identify small molecule perturbations which reverse the gene expression signature induced by CLCN5 KO in the Kidney cell type.
Analysis URLhttp://amp.pharm.mssm.edu/L1000CDS2/#/result/58d202e0e467bea600fba2c2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorshvetank
CREEDS IDgene:997
Cell TypeKidney
Gene Symbol (human)CLCN5
Gene Symbol (mouse)Clcn5
Organismmouse
Perturbation TypeKO
L1000CDS2 parameters
Directionreverse
Characteristic Direction parameters
Control SamplesGSM256959, GSM256960, GSM256961
Perturbed SamplesGSM256956, GSM256957, GSM256958
Tools used in the analysis
Dataset Accession
L1000CDS2
Published August 2016
An ultra-fast LINCS L1000 Characteristic Direction signature search engine
7756
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10162
Gene Expression Omnibus
Dent disease model: renal proximal tubules
12
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