Enrichment analysis of genes dysregulated in IDH2 R140Q Allele
Canned Analysis
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General Information
AccessionDCA00024119
TitleEnrichment analysis of genes dysregulated in IDH2 R140Q Allele
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between IDH2 R140Q Allele cells and control cells in the Heart tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3096358
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1119
Cell TypeHeart tissue
Gene Symbol (human)IDH2
Gene Symbol (mouse)Idh2
Organismmouse
Perturbation TypeR140Q Allele
Characteristic Direction parameters
Control SamplesGSM1324881, GSM1324882, GSM1324883, GSM1324884
Perturbed SamplesGSM1324885, GSM1324886, GSM1324887, GSM1324888
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54838
Gene Expression Omnibus
Heart response to isocitrate dehydrogenase 2 mutations IDH2R140Q and IDH2R172K
7
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