Enrichment analysis of genes dysregulated in IRAK4 IRAK4 kinase deficient mutant
Canned Analysis
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General Information
AccessionDCA00024134
TitleEnrichment analysis of genes dysregulated in IRAK4 IRAK4 kinase deficient mutant
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between IRAK4 IRAK4 kinase deficient mutant cells and control cells in the bone-marrow derived macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3089891
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1131
Cell Typebone-marrow derived macrophages
Gene Symbol (human)IRAK4
Gene Symbol (mouse)Irak4
Organismmouse
Perturbation TypeIRAK4 kinase deficient mutant
Characteristic Direction parameters
Control SamplesGSM229589, GSM229590
Perturbed SamplesGSM229595, GSM229596
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE9037
Gene Expression Omnibus
response to LPS of WT and IRAK4 kinase dead mouse bone marrow macrophages
7
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