Enrichment analysis of genes dysregulated in BRCA1 stable BRCA1 transfection of BRCA1-null cells
Canned Analysis
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General Information
AccessionDCA00024141
TitleEnrichment analysis of genes dysregulated in BRCA1 stable BRCA1 transfection of BRCA1-null cells
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between BRCA1 stable BRCA1 transfection of BRCA1-null cells cells and control cells in the HCC1937 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3095381
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1137
Cell TypeHCC1937
Gene Symbol (human)BRCA1
Gene Symbol (mouse)Brca1
Organismhuman
Perturbation Typestable BRCA1 transfection of BRCA1-null cells
Characteristic Direction parameters
Control SamplesGSM764323, GSM764324, GSM764325
Perturbed SamplesGSM764320, GSM764321, GSM764322
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE30821
Gene Expression Omnibus
Integration of BRCA1-mediated miRNA and mRNA signatures reveal miR-146a, miR-99b and miR-205 regulation of the TRAF2 and NFkB pathways (mRNA dataset)
7
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